AlphaGenome is Google DeepMind's 2026 unifying AI model for decoding the regulatory genome, processing up to 1 million base pairs of DNA to predict thousands of functional tracks at single-base resolution—including gene expression, splicing, chromatin accessibility, histone mods, TF binding, contact maps & more. It achieves SOTA on 25/26 variant effect benchmarks, trained on human/mouse genomes. Non-commercial API access available (with SDK), model weights/code on GitHub—ideal for researchers studying disease variants, gene regulation, synthetic biology. Not for clinical use or ML training.

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